NFL Picks Straight Up: Week 2, 2023 (2024)

Week 2 of the NFL season is upon us, and we've used our powerful predictive analytics model to give you straight up NFL picks for all 16 games.

Gain the edge in NFL pick 'em competitions via our data-driven NFL picks for Week 2 of the 2023 NFL season. These picks are based on over 10,000 simulations of each NFL game.

There are 16 games on the slate for Week 2 of the 2023 NFL season, starting with the Minnesota Vikings playing the Philadelphia Eagles on Thursday night and ending with the Cleveland Browns meeting the Pittsburgh Steelers on Monday night.

These straight up picks for Week 2 are proudly sponsored by Bet365, which has a great Bet $1, Get $365 in Bonus Bets promo for new customers.

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Straight Up NFL Picks - Week 2

Listed below are our Week 2 NFL predictions, which show how likely it is that each NFL team will win its game this week.

Minnesota Vikings vs. Philadelphia Eagles

The Vikings play the Eagles at Lincoln Financial Field on Thursday night to start Week 2. According to our model, the Eagles have a 73% chance of winning, while the Vikings have a 27% chance.

When looking at player props for the opening game of Week 2, our model projects Justin Jefferson (WR) as the most likely player from the Vikings to score the first TD in the game with a probability of 11.6%, while Jalen Hurts(QB) is the most likely from the Eagles at 12.8%.

Minnesota Vikings vs. Philadelphia Eagles is at Lincoln Financial Field on Thursday, September 14 at 8:15pm EDT.

All times mentioned in this article are in Eastern Daylight Time (EDT).

Chicago Bears vs. Tampa Bay Buccaneers

In this week's game between the Bears and the Buccaneers, Tampa Bay is more likely to win. Our prediction model gives the Buccaneers a 57% chance of winning. On the other hand, there is a 43% chance that the Bears will win.

Chicago Bears vs. Tampa Bay Buccaneers is at Raymond James Stadium on Sunday, September 17 at 1:00pm.

MORE: Super Bowl Odds

Green Bay Packers vs. Atlanta Falcons

We are picking the Packers to win their game against the Falcons this week, with our famous NFL model projecting a 54% win probability for the road team. The Falcons have a 46% chance of winning at Mercedes-Benz Stadium.

If you're looking to bet on this clash, Bet365 has the Falcons listed as +2 underdogs, whilst the Packers' moneyline odds are at -120.

Green Bay Packers vs. Atlanta Falcons is at Mercedes-Benz Stadium on Sunday, September 17 at 1:00pm.

Indianapolis Colts vs. Houston Texans

According to our predictive analytics model, the Colts are the team to beat in this game, with their win probability at 54%. The Texans, on the other hand, have a 46% chance of winning.

Indianapolis Colts vs. Houston Texans is at NRG Stadium on Sunday, September 17 at 1:00pm.

MORE: NFL Best Bets

Seattle Seahawks vs. Detroit Lions

The Lions have a 69% chance of winning on Sunday afternoon, compared to the Seahawks' 31% chance of victory. This makes the Detroit Lions our pick to win at Ford Field.

Seattle Seahawks vs. Detroit Lions is at Ford Field on Sunday, September 17 at 1:00pm.

Los Angeles Chargers vs. Tennessee Titans

The Chargers are favorites to win this game, with our predictive analytics model giving them a 66% chance, while the Titans enter the weekend with a 34% chance of causing an upset at Nissan Stadium.

When it comes to betting on this game, Bet365 has the Chargers' moneyline odds set at -155, with the home team Titans listed as +3 underdogs.

Los Angeles Chargers vs. Tennessee Titans is at Nissan Stadium on Sunday, September 17 at 1:00pm.

Baltimore Ravens vs. Cincinnati Bengals

After 10,000 simulations of Ravens vs. Bengals this Sunday, our model projects the Bengals as the more likely winners with a probability of 61%. Their opponents the Ravens have a 39% chance of getting the win on the road.

Baltimore Ravens vs. Cincinnati Bengals is at Paycor Stadium on Baltimore, September 17 at 1:00pm.

MORE: NFL Player Props

Las Vegas Raiders vs. Buffalo Bills

DimersBOT is picking the Bills in this game, with the Bills given a 79% chance of winning, while the Raiders have a 21% win probability.

Las Vegas Raiders vs. Buffalo Bills is at Highmark Stadium on Sunday, September 17 at 1:00pm.

Kansas City Chiefs vs. Jacksonville Jaguars

The next game of Week 2 sees the Chiefs take on the Jaguars at TIAA Bank Field.

We are predicting the Chiefs to win with probability of 58%, while the Jaguars are projected to have a win chance of 42%.

As for the Vegas betting odds here, Bet365 has the Jaguars listed as +3 underdogs, with the Chiefs' moneyline odds posted at -158.

Kansas City Chiefs vs. Jacksonville Jaguars is at TIAA Bank Field on Sunday, September 17 at 1:00pm.

San Francisco 49ers vs. Los Angeles Rams

The likely winner of this matchup is the 49ers who have a projected win chance of 77% according to DimersBOT. On the other side of this matchup, the Rams have a projected win probability of 23%.

San Francisco 49ers vs. Los Angeles Rams is at SoFi Stadium on Sunday, September 17 at 4:05pm.

MORE: Best NFL Bets Today

New York Giants vs. Arizona Cardinals

We have run our powerful NFL model over this week’s Giants-Cardinals clash 10,000 times, with the Giants coming out as the team to pick. Of those 10,000 simulations, the Giants won 7,423 times, with the Cardinals winning on 2,577 occasions.

New York Giants vs. Arizona Cardinals is at State Farm Stadium on Sunday, September 17 at 4:05pm.

New York Jets vs. Dallas Cowboys

Next up is the game between the Jets and Cowboys, with our model projecting the home team as the more likely victor, with Cowboys rated as a 82% chance of getting the W. The Jets on the other hand are projected to have a 18% chance of winning.

For those interested in betting on this matchup, Bet365 has the Jets' moneyline odds set at +350 for this road game, whilst the hosting Cowboys are listed as -9.5 favorites.

New York Jets vs. Dallas Cowboys is at AT&T Stadium on Sunday, September 17 at 4:25pm.

Washington Commanders vs. Denver Broncos

Our next straight up pick this week is for the Broncos to get the win against the Commanders. After running 10,000 simulations of this matchup, the Denver have a win probability of 66%, with the Commanders at 34%.

Washington Commanders vs. Denver Broncos is at Empower Field at Mile High on Sunday, September 17 at 4:25pm.

Miami Dolphins vs. New England Patriots

With a win probability of 58% on Sunday night, our staight up pick for this game is the Dolphins, while their opponent, the Patriots, have a projected win chance of 42%.

Miami Dolphins vs. New England Patriots is at Gillette Stadium on Sunday, September 17 at 8:20pm.

MORE: NFL Player Prop Picks for Week 2

New Orleans Saints vs. Carolina Panthers

The team to pick here is the Saints who have a 67% chance of winning their matchup against the Panthers this Sunday night.

Looking at the betting odds for this Monday Night Football clash, Bet365 has the Panthers listed as +3 underdogs at home, with the Saints' moneyline odds available at -165.

New Orleans Saints vs. Carolina Panthers is at Bank of America Stadium on Monday, September 18 at 7:15pm.

Cleveland Browns vs. Pittsburgh Steelers

Our pick to win the final game of Week 2 is Browns, who have a win probability of 62%. Their opponents are projected to have a 38% chance of getting the W.

Cleveland Browns vs. Pittsburgh Steelers is at Acrisure Stadium on Monday, September 18 at 8:15pm.

NFL Picks This Week Straight Up [Week 2, 2023]

• Eagles (73% win probability)
• Buccaneers (57%)
• Packers (54%)
• Colts (54%)
• Lions (69%)
• Chargers (66%)
• Bengals (61%)
• Bills (79%)
• Chiefs (58%)
• 49ers (77%)
• Giants (74%)
• Cowboys (82%)
• Broncos (66%)
• Dolphins (58%)
• Saints (67%)
• Browns (62%)

NFL Week 2 Slate and Game Times

• Vikings vs. Eagles(Thursday, 8:15PM ET)
• Bears vs. Buccaneers(Sunday, 1:00PM ET)
• Packers vs. Falcons(Sunday, 1:00PM ET)
• Colts vs. Texans(Sunday, 1:00PM ET)
• Seahawks vs. Lions(Sunday, 1:00PM ET)
• Chargers vs. Titans(Sunday, 1:00PM ET)
• Ravens vs. Bengals(Sunday, 1:00PM ET)
• Raiders vs. Bills(Sunday, 1:00PM ET)
• Chiefs vs. Jaguars(Sunday, 1:00PM ET)
• 49ers vs. Rams(Sunday, 4:05PM ET)
• Giants vs. Cardinals(Sunday, 4:05PM ET)
• Jets vs. Cowboys(Sunday, 4:25PM ET)
• Commanders vs. Broncos(Sunday, 4:25PM ET)
• Dolphins vs. Patriots(Sunday, 8:20PM ET)
• Saints vs. Panthers(Monday, 7:15PM ET)
• Browns vs. Steelers(Monday, 8:15PM ET)

All times mentioned in this article are in Eastern Daylight Time (EDT).

NFL Week 2 Bye Teams: Who Has a Bye This Week?

All 32 teams are scheduled to play in Week 2 of the 2023 NFL season, which means no team has a bye this week.

NFL Straight Up Picks and Predictions - Week 2

The NFL Week 2 picks straight up in this article are correct at the time of publication and are subject to change.

Dimers is the best site for NFL predictions, and our straight up picks are being used by football fans all over the country.

If you choose to use our NFL straight up picks for betting purposes, it's crucial that you gamble responsibly and know when to stop. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Please note that all of the odds and probabilities on this page are subject to change.

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